“The biology is complex, but not intractable”, great review by Nature Portfolio on the status and future of drugging RNA.
Phenotypic screening and advanced computation have been used to find selective RNA binders. If the tools and biology can be leveraged in synchrony, RNA biology opens the doors for new highly diverse therapeutic targets and mechanisms. From traditional antagonism to precision modulation of RNA processing and RNA stability. The possibilities are nearly endless.
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“The biology is complex, but not intractable”, great review by Nature Portfolio on the status and future of drugging RNA.
Phenotypic screening and advanced computation have been used to find selective RNA binders. If the tools and biology can be leveraged in synchrony, RNA biology opens the doors for new highly diverse therapeutic targets and mechanisms. From traditional antagonism to precision modulation of RNA processing and RNA stability. The possibilities are nearly endless.