Macomics and Ono Pharma partner to develop macrophage-targeting antibody therapy

Mar 23, 2023

Our portfolio company Macomics announces that it has entered into a worldwide drug discovery collaboration agreement with Ono Pharmaceutical (a leader in immuno-oncology) to develop new immuno-oncology antibody drugs against a novel macrophage target of interest in cancer.

Macomics is exploiting the potential of macrophage-based approaches to develop novel precision medicines to target disease specific macrophage biology. Macrophages (TAMs) are often the most abundant immune cell many types of cancer and modulating TAMs can enhance the body’s ability to fight cancer. Macomics will identify and characterise antibody candidates against the novel target of interest. Ono will have an exclusive option to license global rights to the candidates for further development and commercialization. Macomics will receive an up-front payment, R&D funding, and success-based milestone payments, as well as tiered royalties based on global net sales.

Read the full press release here.